Generic Zetia Uk
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Patient Information about ZETIA (zet´-e-a) Generic name: ezetimibe (e-zet´-e-mib) Read this information carefully before you start taking ZETIA® and each time you get more ZETIA. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment.
Continue taking your other cholesterol-lowering medicines unless your doctor tells you to stop. You should generic Zetia Uk with your doctor or pharmacist if you are not sure. The recommended dose is one Ezetimibe 10 mg tablet by mouth once a day. Take this medicine at any time of the day. You can take it with or without food.
If your doctor has prescribed buy Vardenafil along with a statin, both medicines can be taken at the generic Zetia Uk time. If your doctor has prescribed Ezetimibe along with another medicine for lowering cholesterol containing the generic Zetia Uk ingredient colestyramine or any other medicine containing bile acid sequestrant, you should take Ezetimibe at least 2 hours before or 4 hours after taking the bile acid sequestrant, Generic Zetia Uk. If you take more Ezetimibe than you should Please contact your doctor or pharmacist if you take more Ezetimibe than you should. If you forget to take Ezetimibe Do not take a generic Zetia Uk dose to make up for a forgotten tablet, just take your normal amount of Ezetimibe at the usual time the next day.
If you stop taking Ezetimibe Talk to your doctor or pharmacist because your cholesterol may rise again. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Generic Zetia Availability
Possible generic Zetia Uk effects Like all medicines, this medicine can cause side effects, although not everybody gets them. The following terms are used to describe how often side effects have been reported: Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness.
This is because on rare occasions, muscle problems, including muscle breakdown resulting in kidney cheap Mobic can be serious and may become a potentially life-threatening condition. When used alone, the following side effects were reported: Additionally, when used with a statin, the generic Zetia Uk side effects were reported: When used with fenofibrate, the following common side effect was reported: Additionally, the following side effects have been reported in general use: Reporting of generic Zetia Uk effects If you get any side effects, talk to your doctor or pharmacist.
This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: The liver can synthesize cholesterol, take up cholesterol from the blood from circulating lipoproteins, or take up cholesterol absorbed by the small intestine. Intestinal cholesterol is derived primarily from cholesterol secreted in the bile and from dietary cholesterol.
Generic for Zetia* (Ezetimibe) is prescribed to lower cholesterol in people with high cholesterol levels. This cholesterol-lowering medication is used in combination with a regimen of diet, exercise, and weight loss. By reducing the absorption of cholesterol in the small
Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compounds statins, bile acid sequestrantsfibric generic Zetia Uk derivatives, Generic Zetia Uk, and plant stanols. The molecular target of ezetimibe has been shown to be the sterol transporter, Niemann-Pick C1-Like 1 NPC1L1, which is involved in the intestinal uptake of cholesterol and phytosterols. Ezetimibe does not inhibit cholesterol synthesis in the liver, or increase bile acid excretion. This causes a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the blood; this distinct mechanism is complementary to that of statins and of fenofibrate.
In addition, decreased levels of HDL -C are associated with the development of atherosclerosis. Epidemiologic studies have established that cardiovascular morbidity and mortality vary directly with the level of total-C and LDL-C and inversely with the generic Zetia Uk of HDL-C. Like LDL, cholesterol-enriched triglyceride-rich lipoproteins, including very-low-density lipoproteins VLDL, intermediate-density lipoproteins IDL, and remnants, can generic Zetia Uk promote atherosclerosis. The independent effect of raising HDL-C or lowering TG on the risk of coronary and cardiovascular morbidity and mortality has not been determined.
The effects of ezetimibe generic Zetia Uk either alone or in addition to a statin or fenofibrate on cardiovascular morbidity and mortality have not been established. There was no substantial deviation from dose proportionality between 5 and 20 mg.
Metabolism And Excretion Ezetimibe is generic Zetia Uk metabolized in the small intestine and liver via glucuronide conjugation a phase II reaction with subsequent biliary and renal excretion. Minimal oxidative metabolism a phase I reaction has been observed in all species evaluated. In humans, ezetimibe is rapidly metabolized to ezetimibe-glucuronide.
- The independent effect of raising HDL-C or lowering TG on the risk of coronary and cardiovascular morbidity and mortality has not been determined.
- Ezetimibe, the active ingredient of Ezetimibe, works by reducing the cholesterol absorbed in your digestive tract.
- Ezetimibe does not help you lose weight How to take Zetia Always take this medicine exactly as your doctor has told you.
Both ezetimibe and ezetimibe-glucuronide are eliminated from plasma with a half-life of approximately 22 hours for both ezetimibe and ezetimibeglucuronide.